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http://sandwalk.blogspot.com/2007/07/quinine-and-malaria.html Someone posted something about the quinine mechanism. Thats how it actually destroys P. falciparum.

Quinine works against Plasmodia falciparum (and I suppose other Plasmodia) by preventing the Plasmodia from protecting itself against haem. Haem, which is a byproduct of the breakdown of haemoglobin, which Plasmodia consume, is poisonous and so Plasmodia store this in a vacuole, so they can...

Don't forget that phagocytosis and other non-specific defences are still active during the immune response (3rd Line of Defense).