For the majority of high school science experiments, the line of best fit is expected to be a straight line with the ‘least squares’ such that the square root of the sum of the squares of the distances of each data point to the line is the lowest possible value. Without Excel or some other form of statistical software, at best, you can only draw the line (with a ruler) by visual estimation.
There are also tests of linearity which are extremely tedious to calculate manually, but again Excel and statistical software are easy to use. These software will calculate whether a straight line or a curve (and the order of the polynomial equation for the curve which is the best fit) is a better fit for the data, but I don’t think that’s expected at high school level.