Hi all!
There are a few things I'm trying to wrap my head around in terms of the second and third line of defenses.
First off, how is the lymph system related to the second line of defense? I've read different books and notes. They all agree that lymph nodes store and secrete lymphocytes to produce a specific immune response, so it clearly relates to the third line of defense, but how does it non-specifically react against any antigen or microbe?
Also, "Biology: the spectrum of life" says that phagocytosis is a precursor to a specific immune response because macrophages have histocompatibility markers that recognise antigens, process and present them to helper T-cells that activate cytotoxic T-cells. What are the chances of this link being examined in a HSC exam and how important is it to remember?
Finally, where are the B-cells and T-cells produced? I always get muddled up as to which one is produced in the bone marrow and which one matures in the thymus gland?
Ps. I know defence is spelt with a "c" instead of an "s" but I'm too lazy to combat the autocorrect!
Cheers!
There are a few things I'm trying to wrap my head around in terms of the second and third line of defenses.
First off, how is the lymph system related to the second line of defense? I've read different books and notes. They all agree that lymph nodes store and secrete lymphocytes to produce a specific immune response, so it clearly relates to the third line of defense, but how does it non-specifically react against any antigen or microbe?
Also, "Biology: the spectrum of life" says that phagocytosis is a precursor to a specific immune response because macrophages have histocompatibility markers that recognise antigens, process and present them to helper T-cells that activate cytotoxic T-cells. What are the chances of this link being examined in a HSC exam and how important is it to remember?
Finally, where are the B-cells and T-cells produced? I always get muddled up as to which one is produced in the bone marrow and which one matures in the thymus gland?
Ps. I know defence is spelt with a "c" instead of an "s" but I'm too lazy to combat the autocorrect!
Cheers!