The fact that the second term is '-1' means that the 2nd, 4th, and 6th co-efficients will be negative whilst the 1st, 3rd, and 5th will be positive. Hence the highest co-efficient is either the 1st, 3rd, or 5th.
Now consider Pascal's triangle, for 6 terms: 1, 5, 10, 10, 5, 1.
Also consider the powers of 2 for the 1st, 3rd, and 5th terms:
1st term = 2^5
3rd term = 2^3
5th term = 2^1.
Hence it is obvious that the 3rd term is the highest co-efficient. Which is
.