ok next question brief points about contribution of pasteur and Koch
Pasteur did many things:
1. He studied the use of vaccines. He took 50 sheep and inoculated 25 of them with a weakened strain of anthrax. After about 10 days, he inoculated all 50 with a strong dose of the anthrax, which just as he predicted, killed the 25 sheep which were not injected with a weakened strain of the disease. This was the first recorded/ scientific use of vaccine (it was done before by the Chinese, who ground smallpox scabs and ate them).
2. He disproved the spontaneous generation belief of his time. He poured nutrient broth into two swan necked flasks. He boiled the both flasks to kill off any microbes already present (pasteurisation). He then broke the 'neck' of one of the flasks and placed both in an open area. He found that the flask with the 'broken neck' had developed germs or whatever, and so suggested the germ theory.
Koch:
Koch studied the cause of anthrax in sheep also. He isolated the blood of a sheep and noticed that there were microbes in there that usually wouldn't be. He then cultured the microbes and injected them into another sheep. He found this one had also become infected. He removed the blood yet again and found the same microbes were present as before. He then suggested the 'Postulates' for identifying a certain microbe as cause of a disease:
1. The microbe must be present in the blood of an infected animal.
2. The microbe must be isolated and cultured.
3. If injected into a healthy animal, the microbe must cause the disease.
4. When isolated again, it should be the same microbe as that in the first animal
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Q. the dot point on malaria lol, I can't be bothered writing it